Screen readers go a step beyond text-to-speech. They do read aloud what's on screen, but importantly, screen readers are designed so that you can use them even if you can't see your computer screen.
XDA Developers on MSN
E-readers make terrible second monitors, and that's exactly why I use one for work
You'd never think to use an ePaper screen with your PC, but the reasons for that might be exactly why you should.
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