Unique instruments automate sample preparation, quality control for cryo-electron microscopy

Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...
Paste

Chance the Rapper wins $35 in lawsuit against former manager

Chicago musician Chance the Rapper (born Chancelor Bennett) has won $35 in a five-year legal battle against his onetime manager, Pat Corcoran (formerly known as Pat the Manager). On Friday, a Cook ...
Investopedia

Volatility: Meaning in Finance and How It Works With Stocks

Adam Hayes, Ph.D., CFA, is a financial writer with 15+ years Wall Street experience as a derivatives trader. Besides his extensive derivative trading expertise, Adam is an expert in economics and ...
IEEE

Mixture Density Function Estimation in Shape Clustering

Abstract: Recent developments in measurement tools have made it easier to obtain shape data, a collection of point coordinates in vector space that are meaningful when some of them are gathered ...
Scientific American

Professional Poker Players Know the Optimal Strategy but Don’t Always Use It

“All in.” Your opponent slides a stack of chips across the high-stakes poker table. You glance back at your cards, a pair of sixes. The game is Texas Hold’em. Only two of you remain, and no community ...
Paste

Why Does Every Romance Novel Have the Same Cartoon Cover Right Now?

If you’re a romance reader, or you’ve been in the vicinity of a bookstore anytime over the past couple of years, you’re probably familiar with this trend. Go to the display with the sign reading some ...
C&EN

Ensemble Reweighting Using Cryo-EM Particle Images

Center for Computational Mathematics, Flatiron Institute, New York, New York 10010, United States Center for Computational Biology, Flatiron Institute, New York, New York 10010, United States Article ...
PNAS

Autocorrelation analysis for cryo-EM with sparsity constraints: Improved sample complexity and projection-based algorithms

Cryoelectron microscopy is an imaging technique for determining molecular structures from randomly oriented projection images, with important applications in basic science and drug design. A large ...
Frontiers

Causal Inference in Radiomics: Framework, Mechanisms, and Algorithms

The widespread use of machine learning algorithms in radiomics has led to a proliferation of flexible prognostic models for clinical outcomes. However, a limitation of these techniques is their ...
GitHub

HGS-CVRP: A modern implementation of the Hybrid Genetic Search for the CVRP

This is a modern implementation of the Hybrid Genetic Search (HGS) with Advanced Diversity Control of [1], specialized to the Capacitated Vehicle Routing Problem (CVRP). This algorithm has been ...
Searchenginejournal.com

How The LinkedIn Algorithm Works & Optimizing For It

My first introduction to LinkedIn was in my senior year of college, when it was a requirement of my Career Preparation class to complete a LinkedIn profile. I remember putting up a recent selfie ...
jmg.bmj

Update and audit of the St George’s classification algorithm of primary lymphatic anomalies: a clinical and molecular approach to diagnosis

Correspondence to Professor Sahar Mansour, SW Thames Regional Genetics Service, St George's Hospital, London SW17 0RE, UK; smansour{at}sgul.ac.uk Primary lymphatic anomalies may present in a myriad of ...