Drug peptides defy shape rules, activating receptors without full spiral form

When many of us think about how drugs work in the body, we may first think about how a drug gets into the body, such as a pill versus an injection. In the Gellman Group at the UW–Madison Department of ...

Faster aptamer screening finds synthetic alternatives to antibodies in days instead of months

Aptamers are short DNA or RNA strands that can recognize and bind to a specific target molecule with high precision. Similar ...
Edex Live on MSN

IIT Kanpur researchers make breakthrough in drug receptor research

IIT Kanpur researchers solve mystery of atypical drug target receptor ...
Nature

Two residues reprogram immunity receptors for nitrogen-fixing symbiosis

The lack of symbiotic functionality was further confirmed in an independent experiment in which the synthetic coupling of receptor 3 to NFR5 using the nanobody-mediated strategy for receptor complex ...
Nature

The Arabidopsis MIK2 receptor elicits immunity by sensing a conserved signature from phytocytokines and microbes

Peptide signals generated during plant microbe interactions can trigger immune responses in plants. Here the authors show that SCOOP12, a member of a family of peptides present in Brassicaceae plants, ...