Caveolae are invaginated plasma membrane nanodomains traditionally associated with membrane trafficking and signalling. These multifunctional organelles are also essential mechanosensors mediating the ...

The color in the grid plot corresponds to the likelihood of the compound targeting a viral protein that ranges from low to high (orange-white-blue) using the known inhibitor as reference data (white).

In the RMSD plot of the independent simulations (see Figure 4 A), these conformers can be found in those frames where an RMSD ≤ 0.2 nm is reached. The most representative poses of each of these ...