Novel immune reprogramming oral macrocyclic peptides designed for precise modulation of complex biological networks involved in inflammatory, autoimmune and fibro-inflammatory diseases ...

Effects of resorcinol isoprenyl benzene derivative IPI201 on natural killer cell cytotoxicity and tumor cell viability in human colorectal adenocarcinoma cells. An LNP-mRNA–based in vivo cell engager ...

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Microglia, being the resident immunological sentinels of the central nervous system (CNS), play a critical role in both the pathogenesis and progression of CNS health and disease. In sepsis-associated ...

Unlock the full InfoQ experience by logging in! Stay updated with your favorite authors and topics, engage with content, and download exclusive resources. Martin Kleppmann, an associate professor at ...

Summary: Researchers have demonstrated that memory decline and symptoms of Alzheimer’s may not be irreversible. By using “partial reprogramming” on specific groups of neurons called engrams—the cells ...

Who said free-to-air TV was in its death throes? When the Seven news network ran a piece about Paradigm Biopharmaceuticals’ (ASX:PAR) knee osteoarthritis (OA) drug candidate a few months ago, the ...

The accumulation of lactate in synovial microenvironment of rheumatoid arthritis (RA) patients is closely correlated with disease activity, with elevated lactate levels serving as both biomarkers and ...

The era of AI-powered programming is upon us, and it’s not just a supporting act; it’s stealing the limelight. AI is already rewriting the rules of code creation. However, this is just the tip of the ...