Nuclear Pore Complexes (NPCs) regulate bidirectional transport between the nucleus and the cytoplasm. Intrinsically disordered FG-Nups line the NPC lumen and form a selective barrier, where transport ...
Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K. Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University ...
A K721M kinase-null EGFR mutant did not enter the very slow state even after extended periods (∼100 s) (Fig. 2b). Thus, the EGF-induced very slow state probably correlated with receptor activation.