Toward experiment-guided AlphaFold: Researchers overcome AI tool's single-conformation limitation

The AI-based program AlphaFold predicts a protein's 3D structure with remarkable accuracy. However, it tends to reduce heterogeneous structures to a single dominant conformation, or shape, and ...
The Scientist

Postdoc Portrait: Denis Turcu Explores How Neural Circuit Constraints Shape Brain Function

Allen Institute and University of Washington postdoctoral researcher Denis Turcu uses computational models to study how the ...