The Africa Program achieves its mission through in-depth research that offers practical solutions to key challenges in US-Africa relations. The Africa Program's flagship initiatives include the ...

Genomic prediction is a powerful approach for improving genetic gain and shortening the breeding cycles in animal and crop breeding programs. A series of statistical and machine learning models has ...

The Indo-Pacific Program promotes policy debate and intellectual discussions on US interests in the Asia-Pacific as well as political, economic, security, and social issues relating to the world’s ...

Relative binding free energy calculations have become an integral computational tool for lead optimization in structure-based drug design. Classical alchemical methods, including free energy ...

LaDyBUGS is an efficient alchemical free energy method for computing free energy differences between two or more chemical states. LaDyBUGS uses Gibbs sampling to sample alchemical transformations ...

particle filtering: bootstrap filter, guided filter, APF. resampling: multinomial, residual, stratified, systematic and SSP. possibility to define state-space models using some (basic) form of ...

Multidimensional surfaces of quantum chemical properties, such as potential energies and dipole moments, are common targets for machine learning, requiring the development of robust and diverse ...

The performance comparison of reconstructed and enriched networks with that of the original networks is first carried out by leave-one-out validation. The top protein function prediction is selected ...

Immiscible fluids are found everywhere—examples include vinaigrette and ouzo in the kitchen, multiphase hydrocarbon–water mixtures common in oil extraction, and in virtually all living things. Within ...