The longitudinal propagation of water-quality and ecological impairments in rivers during and after wildfires remain poorly understood. In Northern California, the 2022 McKinney Fire burned 243 km 2 ...
Aims: Sodium-glucose cotransporter-2 (SGLT2) inhibitors have been found to ameliorate major adverse cardiovascular events in patients with heart failure with preserved ejection fraction (HFpEF), but ...
Chronic lung inflammation triggered by dysregulated activation of innate immunity is implicated in pulmonary emphysema. However, key innate immune molecular regulators that trigger emphysema remain ...
Mutations in PIEZO1 (Piezo type mechanosensitive ion channel component 1) cause human lymphatic malformations. We have previously uncovered an ORAI1 (ORAI calcium release-activated calcium modulator 1 ...
Close-packed hexagonal array nanopores are widely used both in research and industry. A self-ordered nanoporous structure makes anodic aluminum oxide (AAO) one of the most popular nanomaterials. This ...
Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss among the elderly in developed countries. It is estimated that there will be 288 million AMD patients by 2040 ...
Most in vitro test systems for the assessment of toxicity are based on endpoint measurements and cannot contribute much to the establishment of mechanistic models, which are crucially important for ...
Insulin-like growth factor 1 (IGF1) plays an important role in the regulation of metabolism and growth. Epidemiological studies revealed that IGF1 deficiency is associated with cancer protection.
Vascular calcification is prevalent in the aging population, yet little is known of the mechanisms driving age-associated vascular smooth muscle cell (VSMC) phenotypic change. Prelamin A, the ...
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